The Bacterial Vaccines department is recruiting a qualified Associate scientist in Glycoconjugate purification and analysis for a major vaccine project. In the course of your work, you will interact with various Bacterial Vaccines teams, and with Janssen Vaccines support departments. You will be expected to perform laboratory work fulltime.
In the context of biochemical development and analysis, which are centered mainly on the production and analysis of carbohydrate-protein conjugates and peptide-protein conjugates your main responsibilities will be: o Supervising production and evaluation of carbohydrate-protein conjugates. o Act as an expert on characterization of glycoproteins o Devise in-process controls to monitor the glycoconjugation process o Support development of new conjugation methods o Data acquisition and evaluation o Fairly independent work without day-to-day supervision o Managing a small team of junior/associate scientists o Reviewing the progress of work at a contract research partner (CRO/CMO) o Manage/supervise downstream processing of glycoconjugates (together with the BacVac Bioprocess team) We are looking for a professional with the following Background
PhD/advanced engineering degree or equivalent, in a relevant discipline such as bioorganic chemistry, bioanalytical technologies, pharmaceutical technology, biochemistry, biochemical engineering or related fields.
Experienced Msc is not ruled out
Preferably two years of professional experience (biotechnology/pharmaceutical industry is a plus).
A strong background on downstream processing of glycoconjugate proteins is a must.
Previous experience working with carbohydrates, proteins, and glycoproteins is a must.
Previous experience working with bioconjugation reactions (e.g. labelling, chemical modifications), and (bio)chemical analysis (e.g. HPLC) is highly valuable.
Hands-on experience on advanced glycoprotein characterization methods is highly valuable.
Previous experience in drafting technical process descriptions, process SOPs and biochemical process flow diagrams is highly desirable.
you are a team player, flexible, motivated who communicates clearly.
Language skills: fluent English. Dutch considered a plus
Computer skills (MS Office, ChemDraw, etc.)
Planning, organizing and executing work accurately and efficiently. LabResource is the top tier supplier of Janssen Vaccines and Prevention BV, one of the Janssen Pharmaceutical Companies of Johnson & Johnson. Janssen is dedicated to bringing meaningful innovation to global health. Consultant name: Thijs RemijnConsultant phone: +31204069750
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